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Sunday, August 9, 2020 | History

3 edition of Nucleic acid therapeutics in cancer found in the catalog.

Nucleic acid therapeutics in cancer

Nucleic acid therapeutics in cancer

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  • 39 Currently reading

Published by Humana Press in Totowa, N.J .
Written in English

    Subjects:
  • Antisense nucleic acids -- Therapeutic use.,
  • Cancer -- Chemotherapy.,
  • Neoplasms -- therapy -- Congresses.,
  • Gene Therapy -- methods -- Congresses.,
  • Nucleic Acids -- therapeutic use -- Congresses.

  • Edition Notes

    Statementedited by Alan M. Gewirtz.
    GenreCongresses.
    SeriesCancer drug discovery and development
    ContributionsGewirtz, A. M.
    Classifications
    LC ClassificationsRC271.A69 N83 2004
    The Physical Object
    Pagination219 p. :
    Number of Pages219
    ID Numbers
    Open LibraryOL21801834M
    ISBN 101588292584
    LC Control Number2003025020

    Nucleic acid delivery for cancer holds extraordinary promise. Increasing expression of tumor suppressor genes or inhibition of oncogenes in cancer cells has important therapeutic potential. However, several barriers impair progress in cancer gene delivery. These include effective delivery to cancer cells and relevant intracellular compartments. Although viral gene delivery can be effective, it Cited by:   Early assessment of nucleic acid function was rather narrow and restricted, but research in the past few decades has seen remarkable progress in developing nucleic acid‐based therapeutics. The progress has covered diverse fields of research and a significant number of scientists and engineers are now involved in this area by:

      Nucleic Acid Aptamers for Molecular Diagnostics and Therapeutics: Advances and Perspectives. Weihong Tan. Corresponding Author. E-mail address: distinguish between the target leukemia cells and other cancer cells within the matrix of heterogeneity, which characterizes cancer .   Aptamers can mediate nucleic acid therapy by increasing nucleic acid targeting efficacy for oncogenes and supressing overexpressed signalling molecules or regulatory nucleic acids in cancer , , Intense effort has been devoted to explore aptamers as an effective nucleic acid therapy modality for cancer by:

    Cancer immunotherapy has shown great potential as witnessed by an increasing number of immuno-oncology drug approvals in the past few years. Meanwhile, the field of nucleic acid therapeutics has. Advances in Nucleic Acid Therapeutics (ISSN Book 68) - Kindle edition by Sudhir Agrawal, Michael J Gait, Marvin H Caruthers, David Corey, Eric Swayze, Richard Geary, Annemieke Aartsma-Rus, Derick Wansink, Jonathan Hall, Claes Wahlestsedt, Anastasia Khvorova, Mano Manoharan, John Rossi, Kensuke Miyake, Paloma Giangrande, Gerald Zon, Carine Giovannangeli, Sabine Müller, Yogesh 5/5(1).


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Nucleic acid therapeutics in cancer Download PDF EPUB FB2

Concise yet highly readable, Nucleic Acid Therapeutics in Cancer offers those who require a cutting-edge critical synthesis not only a state-of-the-art account of this promising field, but also an illuminating introduction to their emerging therapeutic : Hardcover.

Concise yet highly readable, Nucleic Acid Therapeutics in Cancer offers those who require a cutting-edge critical synthesis not only a state-of-the-art account of this promising field, but also an illuminating introduction to their emerging therapeutic uses.

Download the eBook Nucleic Acid Therapeutics in Cancer (Cancer Drug Discovery and Development) in PDF or EPUB format and read it directly on your mobile phone, computer or any device. Read "Nucleic Acid Therapeutics in Cancer" by available from Rakuten Kobo.

A cutting-edge review of the important issues underlying the therapeutic use of nucleic acid Brand: Humana Press. Book: Gerwitz AM, ed. Nucleic Acid Therapeutics in Cancer (Cancer Drug Discovery and Development). Humana Press, New York, NY. Chapter in a Book: Rogers FA, Glazer PM.

Targeted genome modification via triple helix formation. In: Nucleic Acid Therapeutics in Cancer (Cancer Drug Discovery and Development). Gerwitz AM, ed. From the book: Advances in Nucleic Acid Therapeutics CHAPTER 15 Prostate-specific Membrane Antigen (PSMA) Aptamers for Prostate Cancer Imaging and Therapy.

Shambhavi Shubham, Li-Hsien Lin, Ofonime Udofot, Sven Krupse and Paloma H. Giangrande Author: Shambhavi Shubham, Li-Hsien Lin, Ofonime Udofot, Sven Krupse, Paloma H.

Giangrande. Interestingly, nucleic acid therapeutics have emerged as a pivotal class of regimen for cancer immunotherapy. Examples of such nucleic acid immunotherapeutics include immunostimulatory DNA/RNA, mRNA/plasmids that can be translated into immunotherapeutic proteins/peptides, and genome-editing nucleic : Tingting Shen, Tingting Shen, Yu Zhang, Yu Zhang, Shurong Zhou, Shuibin Lin, Xiao-bing Zhang, Guizhi.

Nucleic acid therapeutics is a field that has been continually innovating to meet the challenges of drug discovery and development; bringing contributions together from leaders at the forefront of progress, this book depicts the many approaches currently being pursued in both academia and industry.

Nucleic Acid Therapeutics (formerly Oligonucleotides) Co-Editors-in-Chief: Bruce A. Sullenger, PhD and Annemieke Aartsma-Rus, PhD Executive Editor: Graham C. Parker, PhD. Advances in Nucleic Acid Therapeutics Edited by Sudhir Agrawal and Michael J.

Gait Advance Book Information March All information is subject to change without notice Advances in Nucleic Acid Therapeutics Sudhir Agrawal Idera Pharmaceuticals, USA Michael J Gait MRC Laboratory of Molecular Biology (LMB), UK Synopsis. Abstract. Cancer research has found a novel foothold in studying exosomes, the 40– nm membrane-bound vesicles secreted by cells as molecular messengers.

These secreted vesicles of endocytic origin act as signaling conveyors between cells by shuttling molecular cargo in the form of proteins, mRNA, miRNA, and lipids.

Antisense methodology / Fritz Eckstein --Nucleic acid therapeutics / Alan M. Gewirtz --Targeted genome modification via triple helix formation / Faye A. Rogers and Peter M. Glazer --Therapeutic applications of ribozymes / John J.

Rossi --Use of catalytic DNA in target validation and therapeutics / Lun-Quan Sun --Targeted destruction of small. Nucleic Acids as Therapeutics 23 growth factor receptor 2 was confirmed to be capable of tumor suppression by blocking angiogenesis upon intratumoral injections in mice (Zhang et al.

NAR Cancer publishes original research and Survey and Summary articles at the intersection of the nucleic acids research and cancer fields, including cancer computational biology and data resources, DNA damage sensing and repair, gene regulation and chromatin, genomics, methods, nucleic acid-based therapeutics, and structural biology.

Structures of quadruplex nucleic acids and their drug complexes 9. Solvent-accessible surfaces of proteins and nucleic acids Nucleic acid medicines as green novel anticancer drugs Correlation between nucleic acids and nanoparticle therapeutics for cancer treatment Drug delivery systems as advanced nanotechnology Books/eBooks Trade Magazines Nucleic Acid Therapeutics Co-Editors-in-Chief: Bruce A.

Sullenger, PhD and Annemieke Aartsma-Rus, PhD Delivering cutting-edge peer-reviewed research on using nucleic acids and related compounds to alter gene expression for therapeutic purposes. Get this from a library. Nucleic acid therapeutics in cancer. [A M Gewirtz;] -- The development of effectively targeted and efficiently delivered nucleic acids promises important advances in the diagnosis and treatment of human malignancies.

In Nucleic Acid Therapeutics in. The design and development of nucleic acid (NA)-based therapeutics for the treatment of diseases arising from genetic abnormalities have made significant progress.

NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Nucleic Acids Research () Surveys & Summaries. Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNA Shen, X.

and Corey, D.R. Nucleic Acids Research () Splice-switching antisense oligonucleotides as therapeutic drug Havens, M.A. and Hastings, M.L. Nucleic Acids Research (), 44 (14)   Nucleic acid–based functional nanomaterials (NAFN) have been widely used as emerging drug delivery nanocarriers for cancer therapeutics.

Considerable works have demonstrated that NAFN can effectively load and protect therapeutic agents, and particularly enable targeting delivery to the tumor site and stimuli‐responsive by: 4. Abstract.

Gene therapy is a technique for correcting defective genes responsible for disease development. Nucleic acid-based molecules (deoxyribonucleic acid, complementary deoxyribonucleic acid, complete genes, ribonucleic acid, and oligonucleotides) are utilized as research tools within the broad borders of gene therapy and the emerging field of molecular by: Lee "Nucleic Acid Therapeutics in Cancer" por disponible en Rakuten Kobo.

A cutting-edge review of the important issues underlying the therapeutic use of nucleic acid-mediated gene silencing. To Brand: Humana Press.Cover Art: All siRNA, ASO and mRNA therapeutics are taken up into cells by endocytosis; however, escape from the endosome across the endosomal lipid bilayer into the cytoplasm and nucleus remains the rate-limiting step.

This Special Issue on Delivery of RNA Therapeutics takes an in-depth look at state-of-the-art approaches to tackle this significant problem.